Uromodulin modulates the effect of salt on blood pressure in the general population [OP.2A.02]

TitleUromodulin modulates the effect of salt on blood pressure in the general population [OP.2A.02]
Publication TypeConference Paper
Year of Publication2016
AuthorsPonte, B, Pruijm, M, Guessous, I, Ackermann, D, Ehret, G, Mohaupt, M, Paccaud, F, Vogt, B, Martin, PY, Pechere-Berstschi, A, Burnier, M, Devuyst, O, Bochud, M
Conference NameJournal of Hypertension
Date Published01/2016
ISBN Number0263-6352 (ISSN)
Abstract

Objective: Genome wide association studies have shown that the gene encoding for uromodulin (UMOD) is associated with hypertension. Recently, animal studies have demonstrated that UMOD modulates NaCl reabsorption driven by NKCC2. We hypothesised that the NaCl effect on blood pressure may be modulated by UMOD levels in the general population.

Notes

Oral session

URLhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=toc&D=ovft&MODE=ovid&NEWS=N&AN=00004872-000000000-00000
DOI10.1097/01.hjh.0000491367.86585.73
Citation Key / SERVAL IDserval:BIB_E8B482DF3CF6
Peer reviewNon-Refereed

                         

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