A Comparative Analysis of the Status Anxiety Hypothesis of Socio-economic Inequalities in Health Based on 18,349 individuals in Four Countries and Five Cohort Studies.

TitleA Comparative Analysis of the Status Anxiety Hypothesis of Socio-economic Inequalities in Health Based on 18,349 individuals in Four Countries and Five Cohort Studies.
Publication TypeJournal Article
Year of Publication2019
AuthorsLayte, R, McCrory, C, Cheallaigh, CNi, Bourke, N, Kivimaki, M, Ribeiro, AIsabel, Stringhini, S, Vineis, P
JournalScientific reports
Volume9
Issue1
Pagination796
Date Published01/2019
DOI10.1038/s41598-018-37440-7
ISSN2045-2322
Abstract

The status anxiety hypothesis proposes that systematic inflammation as a consequence of chronic psycho-social stress is a possible pathway linking socio-economic position (SEP) to premature ageing and is a possible explanation for cross-national variation in patterns of health and well-being. Harmonised data from the LIFEPATH consortium on 18,349 individuals aged 50 to 75 and 30,632 observations are used to measure variation in the association between inflammation measured as C-reactive protein and SEP across four countries (Britain, Ireland, Portugal and Switzerland) and five studies (ELSA, Whitehall II, TILDA, EPIPorto and SKIPOGH). Adjusting for population composition, mean concentrations of CRP are highest in Portugal, the country with the highest income inequality and lowest in Switzerland, a lower income inequality country. Across all of the studies, lower SEP groups have higher mean concentrations of CRP and, as predicted by the theory, absolute differentials between SEP groups reflect the pattern of societal income inequality. Adjustment for lifestyle indicators reduces SEP differentials by between 45% and 52% but cannot account for country variation in mean inflammation.

Alternate URL

http://www.ncbi.nlm.nih.gov/pubmed/30692559?dopt=Abstract

WOS ID (UT)

000456826200025

Alternate JournalSci Rep
Citation Key / SERVAL ID9371
Peer reviewRefereed
PubMed ID30692559
PubMed Central IDPMC6349896
Grant List633666 / / European Commission (EC) /
633666 / / European Commission (EC) /
633666 / / European Commission (EC) /
633666 / / European Commission (EC) /

                         

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