The relation of body mass index and abdominal adiposity with dyslipidemia in 27 general populations of the WHO MONICA Project.

TitreThe relation of body mass index and abdominal adiposity with dyslipidemia in 27 general populations of the WHO MONICA Project.
Publication TypeJournal Article
Year of Publication2013
AuthorsWietlisbach, V, Marques-Vidal, P, Kuulasmaa, K, Karvanen, J, Paccaud, F
Corporate AuthorsWHO MONICA Project
JournalNutr Metab Cardiovasc Dis
Volume23
Issue5
Pagination432-42
Date Published2013 May
DOI10.1016/j.numecd.2011.09.002
ISSN1590-3729
Mots-clésAdiposity, Adult, Australia, Body Mass Index, Canada, Cholesterol, HDL, Cholesterol, LDL, Cross-Sectional Studies, Dyslipidemias, Europe, Female, Health Surveys, Humans, Logistic Models, Male, Menopause, Middle Aged, New Zealand, Obesity, Abdominal, Prevalence, Risk Factors, Smoking, Triglycerides, Waist Circumference
Abstract

BACKGROUND AND AIMS: The association between adiposity measures and dyslipidemia has seldom been assessed in a multipopulational setting.

METHODS AND RESULTS: 27 populations from Europe, Australia, New Zealand and Canada (WHO MONICA project) using health surveys conducted between 1990 and 1997 in adults aged 35-64 years (n = 40,480). Dyslipidemia was defined as the total/HDL cholesterol ratio >6 (men) and >5 (women). Overall prevalence of dyslipidemia was 25% in men and 23% in women. Logistic regression showed that dyslipidemia was strongly associated with body mass index (BMI) in men and with waist circumference (WC) in women, after adjusting for region, age and smoking. Among normal-weight men and women (BMI84.8 cm) in normal-weight men, menopause in women and regular smoking further defined subgroups at increased risk.

CONCLUSION: standard categories of BMI and WC, or their combinations, do not lead to optimal risk stratification for dyslipidemia in middle-age adults. Sex-specific adaptations are necessary, in particular by taking into account abdominal obesity in normal-weight men, post-menopausal age in women and regular smoking in both sexes.

Alternate URL

http://www.ncbi.nlm.nih.gov/pubmed/22209742?dopt=Abstract

Alternate JournalNutr Metab Cardiovasc Dis
Citation Key / SERVAL ID3168
PubMed ID22209742

                         

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