A comparison of trends in mortality from primary liver cancer and intrahepatic cholangiocarcinoma in Europe.

TitreA comparison of trends in mortality from primary liver cancer and intrahepatic cholangiocarcinoma in Europe.
Publication TypeJournal Article
Year of Publication2013
AuthorsBertuccio, P, Bosetti, C, Levi, F, Decarli, A, Negri, E, La Vecchia, C
JournalAnn Oncol
Volume24
Issue6
Pagination1667-74
Date Published2013 Jun
DOI10.1093/annonc/mds652
ISSN1569-8041
ISBN Number1569-8041 (Electronic)
Mots-clésAustralia, Cholangiocarcinoma, Europe, European Union, Female, Humans, Japan, Liver Neoplasms, Male, Middle Aged, Survival Rate, United States, World Health Organization
Abstract

BACKGROUND: To update and compare mortality from primary liver cancer (PLC) and intrahepatic cholangiocarcinoma (ICC) in Europe in 1990-2010.

MATERIALS AND METHODS: We used data from the World Health Organization (WHO) to compute age-standardized (world population) mortality rates, and used joinpoint analysis to identify substantial changes.

RESULTS: Between 2002 and 2007, PLC rates in the European Union (EU) declined from 3.9 to 3.6/100,000 men. Around 2007, the highest male rates were in France (6.2/100,000), Spain (4.9), and Italy (4.0), while the lowest ones were in Sweden (1.1), the Netherlands (1.2), and the UK (1.8). In women, mortality was lower (0.8/100,000 in 2007 in the EU), and showed more favourable trends, with a decline of over 2% per year over the last two decades as compared with 0.4% in men, in the EU. In contrast, the EU mortality from ICC increased by around 9% in both sexes from 1990 to 2008, reaching rates of 1.1/100,000 men and 0.75/100,000 women. The highest rates were in UK, Germany, and France (1.2-1.5/100,000 men, 0.8-1.1/100,000 women).

CONCLUSIONS: PLC mortality has become more uniform across Europe over recent years, with an overall decline; in contrast, ICC mortality has substantially increased in most Europe.

Notes

Publication types: Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish

Alternate URL

http://www.ncbi.nlm.nih.gov/pubmed/23378539?dopt=Abstract

Alternate JournalAnn. Oncol.
Citation Key / SERVAL ID3391
PubMed ID23378539

                         

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