Factors associated with 24-hour urinary volume: the Swiss salt survey.

TitreFactors associated with 24-hour urinary volume: the Swiss salt survey.
Publication TypeJournal Article
Year of Publication2013
AuthorsSchoen, T, Blum, J, Paccaud, F, Burnier, M, Bochud, M, Conen, D
Corporate AuthorsSwiss Survey on Salt investigators
JournalBMC Nephrol
Date Published2013
Mots-clésAdult, Age Distribution, Biomarkers, Data Collection, Diet Surveys, Female, Food Preferences, Humans, Kidney Function Tests, Male, Middle Aged, Prevalence, Prognosis, Renal Insufficiency, Chronic, Reproducibility of Results, Risk Factors, Sensitivity and Specificity, Sex Distribution, Sodium Chloride, Dietary, Switzerland

BACKGROUND: Low 24-hour urine volume (24 UV) may be a significant risk factor for decline in kidney function. We therefore aimed to study associated markers and possible determinants of 24 UV in a sample of the Swiss population.

METHODS: The cross-sectional Swiss Salt Study included a population-based sample of 1535 (746 men and 789 women) individuals from three linguistic regions of Switzerland. Data from 1300 subjects were available for the present analysis. 24 UV was measured using 24-hour urine collection. Determinants of 24 UV were identified using multivariable linear regression models.

RESULTS: In bivariate analysis, 24 UV was higher in women compared to men (2000 ml/24 h [interquartile range (IQR): 1354, 2562] versus 1780 ml/24 h [IQR: 1244, 2360], p = 0.002). In multivariable regression analyses, independent associated markers of 24 UV were female sex (β = 280, 95% confidence interval [CI]: 174, 386, p

CONCLUSION: In this large population-based, cross-sectional study, we found several strong and independent correlates for 24 UV. These findings may be important to improve our understanding in the development of chronic kidney disease.


Publication types: Journal ArticlePublication Status: epublish

Alternate URL


Alternate JournalBMC Nephrol
Citation Key / SERVAL ID3506
PubMed ID24199987
PubMed Central IDPMC4226251


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