Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account.

TitrePain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account.
Publication TypeJournal Article
Year of Publication2016
AuthorsZeitz, J, Ak, M, Müller-Mottet, S, Scharl, S, Biedermann, L, Fournier, N, Frei, P, Pittet, V, Scharl, M, Fried, M, Rogler, G, Vavricka, S
Corporate AuthorsGroup, SIBDCohort
JournalPLoS One
Volume11
Issue6
Paginatione0156666
Date Published2016
DOI10.1371/journal.pone.0156666
ISSN1932-6203
Mots-clésAdult, Female, Humans, Inflammatory Bowel Diseases/complications, Inflammatory Bowel Diseases/drug therapy, Inflammatory Bowel Diseases/epidemiology, Male, Middle Aged, Pain/complications, Pain/drug therapy, Pain/epidemiology, Quality of Life, Time Factors
Abstract

BACKGROUND: Pain is a common symptom related to inflammatory bowel disease (IBD). In addition to abdominal pain, pain can also be an extraintestinal manifestation of IBD. Pain treatment is challenging and a substantial part of IBD patients are treated with opioids. Therefore, a better knowledge on pain symptoms is crucial for a better therapeutic approach to this clinical problem.

METHODS: Patients of the Swiss IBD Cohort Study (SIBDCS) (n = 2152) received a questionnaire regarding pain intensity, pain localization and impact of pain on daily life and social activities. Furthermore, the questionnaire investigated the use of pain-specific medication.

RESULTS: A vast majority of patients (71%) experienced pain during the disease course. For a substantial part of patients (49% in UC and 55% in CD) pain is a longstanding problem (>5 years). Pain in UC was of shorter duration compared to CD (p < 0.01). Abdominal pain (59.5%) and back pain (38.3%) were the main pain localizations. 67% of patients took pain medication; 24% received no pain treatment. The general quality of life was significantly lower in patients suffering of pain compared to those without pain (38 vs. 77; (-100 very bad; 100 very good) p<0.0001).

CONCLUSIONS: Prevalence of pain is high in patients of the SIBDCS. It is a longstanding problem for the majority of the patients affected. Pain was found to be undertreated in the SIBDCS and was significantly associated with health-related quality of life. Thus, an increased awareness is mandatory to address this frequent complication in the course of IBD.

Alternate URL

http://www.ncbi.nlm.nih.gov/pubmed/27332879?dopt=Abstract

WOS ID (UT)

000378212800013

Alternate JournalPLoS ONE
Citation Key / SERVAL ID7171
PubMed ID27332879
PubMed Central IDPMC4917102
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