Association of disclosure of HIV status with medication adherence

TitreAssociation of disclosure of HIV status with medication adherence
Publication TypeJournal Article
Year of Publication2016
AuthorsRotzinger, A, Locatelli, I, Reymermier, M, Amico, S, Bugnon, O, Cavassini, M, Schneider, MP
JournalPatient Education and Counseling
Type of ArticleJournal Article
Accession NumberPMID:27033978
Mots-clésAdult, Anti-HIV Agents/therapeutic use, Cross-Sectional Studies, Disclosure, Female, HIV, HIV Infections/drug therapy, HIV Infections/psychology, HIV Seropositivity/psychology, Humans, Logistic Models, Longitudinal Studies, Male, Medication adherence, Refusal to participate, Self Disclosure, Social Stigma, Social Support, Socioeconomic Factors, Surveys and Questionnaires, Switzerland, Truth Disclosure

OBJECTIVE: Disclosure may affect adherence to antiretroviral treatment. In a medication adherence program, this cross-sectional study describes disclosure, perceived reaction after disclosure, living situations, and the relationship of disclosure with antiretroviral adherence. METHODS: A combination of a questionnaire to measure disclosure and longitudinal electronic monitoring of medication adherence was used. RESULTS: A total of 103 out of 159 eligible patients gave informed consent. The characteristics differed between participants and nonparticipants (race, education, sexual orientation, medication adherence). Thirteen participants did not disclose their HIV status. Seventy-three (81%) participants judged the reaction after disclosure positive. Among the 62 participants cohabiting, 52% disclosed to all co-residents. Adherence was high (median 100%). HIV disclosure was negatively associated with adherence, when disclosing to the mother (OR=2.46, p-value=0.086) and to siblings (OR=2.89, p-value=0.029). Living alone was associated to a lower adherence than cohabitation (Rate Ratio=1.42, p-value=0.007). CONCLUSION: HIV disclosure and adherence are sensitive issues, which may explain the reason for refusal. Nonparticipants may be those with the most difficulties disclosing. PRACTICE IMPLICATIONS: An unbiased collection of sensitive information, as HIV disclosure, is a difficult task. A cohort design, with research data collected systematically by a trusted healthcare provider, may better describe the association between adherence and disclosure.



Citation Key / SERVAL IDRN19
Peer reviewRefereed


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